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Publication Cover

American Journal of Respiratory and Critical Care Medicine

Table of Contents
Volume 205, Issue 1 | January 1 2022
ISSN: 1073-449X | eISSN: 1535-4970
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Editorials

Advancing Global Respiratory Health, Sleep, and Critical Care: Editorial from the New American Journal of Respiratory and Critical Care Medicine Team
Fernando J. Martinez, Laurent Brochard, Andrew Bush, Gavin Donaldson, and MeiLan K. Han
pp. i–ii
First Page | Full Text | PDF (514 KB) 
Gaining Insights into Asthma-related COVID-19 Risk
Tara F. Carr and Monica Kraft
pp. 1–2
First Page | Full Text | PDF (578 KB) | related article 
From Mass to Flow: Emerging Sepsis Diagnostics Based on Flow Cytometry Analysis of Neutrophils
Franck Verdonk, Joe L. Hsu, and Brice Gaudilliere
pp. 2–4
First Page | Full Text | PDF (575 KB) | related article 
Cut from the Same Cloth: Similarities between Hypersensitivity Pneumonitis and Idiopathic Pulmonary Fibrosis
Monica M. Yang and Paul J. Wolters
pp. 4–6
First Page | Full Text | PDF (574 KB) | related article 
The Future of Outcome Prediction for Preterm Infants in the Neonatal ICU
Colm P. Travers, Waldemar A. Carlo, and Namasivayam Ambalavanan
pp. 6–8
First Page | Full Text | PDF (573 KB) | related article 
Reduced Aerobic Exercise Capacity in Adults Born at Very Low Birth Weight: No Small Matter!
Andrew T. Lovering and Joseph W. Duke
pp. 8–10
First Page | Full Text | PDF (603 KB) | related article 
Preterm Birth Enhances Ambient Pollution Toxicity: Oxidative Stress and Placental Function
Rosalind J. Wright
pp. 10–12
First Page | Full Text | PDF (531 KB) | related article 
Sleep Apnea–Specific Hypoxic Burden and Not the Sleepy Phenotype as a Novel Measure of Cardiovascular and Mortality Risk in a Clinical Cohort
Reena Mehra and Ali Azarbarzin
pp. 12–13
First Page | Full Text | PDF (585 KB) | related article 
2021 American Thoracic Society BEAR Cage Winning Proposal: Microbiome Transplant in Pulmonary Arterial Hypertension
Daphne M. Moutsoglou
pp. 13–16
First Page | Full Text | PDF (573 KB) 

Pulmonary Perspective

Global Initiative for Asthma Strategy 2021: Executive Summary and Rationale for Key Changes
Helen K. Reddel, Leonard B. Bacharier, Eric D. Bateman, Christopher E. Brightling, Guy G. Brusselle, Roland Buhl, Alvaro A. Cruz, Liesbeth Duijts, Jeffrey M. Drazen, J. Mark FitzGerald, Louise J. Fleming, Hiromasa Inoue, Fanny W. Ko, Jerry A. Krishnan, Mark L. Levy, Jiangtao Lin, Kevin Mortimer, Paulo M. Pitrez, Aziz Sheikh, Arzu A. Yorgancioglu, and Louis-Philippe Boulet
pp. 17–35
Abstract | Full Text | PDF (2714 KB) 

Original Articles

COVID-19/Asthma and Allergy

Asthma Phenotypes and COVID-19 Risk: A Population-based Observational Study
Chloe I. Bloom, Paul Cullinan, and Jadwiga A. Wedzicha
pp. 36–45
Abstract | Full Text | PDF (837 KB) | related editorial 

Critical Care

Two New Neutrophil Subsets Define a Discriminating Sepsis Signature
Aïda Meghraoui-Kheddar, Benjamin G. Chousterman, Noëlline Guillou, Sierra M. Barone, Samuel Granjeaud, Helene Vallet, Aurélien Corneau, Karim Guessous, Charles de Roquetaillade, Alexandre Boissonnas, Jonathan M. Irish, and Christophe Combadière
pp. 46–59
Abstract | Full Text | PDF (2755 KB) | related editorial 

Interstitial Lung Disease

Lung Microenvironments and Disease Progression in Fibrotic Hypersensitivity Pneumonitis
Laurens J. De Sadeleer, John E. McDonough, Jonas C. Schupp, Xiting Yan, Arno Vanstapel, Anke Van Herck, Stephanie Everaerts, Vincent Geudens, Annelore Sacreas, Tinne Goos, Celine Aelbrecht, Tim S. Nawrot, Dries S. Martens, Dominique Schols, Sandra Claes, Johny A. Verschakelen, Eric K. Verbeken, Maximilian Ackermann, Anabelle Decottignies, Manon Mahieu, Tillie-Louise Hackett, James C. Hogg, Bart M. Vanaudenaerde, Stijn E. Verleden, Naftali Kaminski, and Wim A. Wuyts
pp. 60–74
Abstract | Full Text | PDF (3674 KB) | related editorial 

Pediatric Critical Care

Hourly Kinetics of Critical Organ Dysfunction in Extremely Preterm Infants
Orlyn C. Lavilla, Khyzer B. Aziz, Allison C. Lure, Daniel Gipson, Diomel de la Cruz, and James L. Wynn
pp. 75–87
Abstract | Full Text | PDF (2669 KB) | related editorial 

Pediatrics and Lung Development

Reduced Exercise Capacity in Adults Born at Very Low Birth Weight: A Population-based Cohort Study
Jun Yang, Michael J. Epton, Sarah L. Harris, John Horwood, Rachel A. Kingsford, Richard Troughton, Charlotte Greer, and Brian A. Darlow
pp. 88–98
Abstract | Full Text | PDF (887 KB) | related editorial 

Pediatrics and Lung Development/Environmental and Occupational Lung Disease

Increased Impact of Air Pollution on Lung Function in Preterm versus Term Infants: The BILD Study
Fabienne Decrue, Olga Gorlanova, Yasmin Salem, Danielle Vienneau, Kees de Hoogh, Amanda Gisler, Jakob Usemann, Insa Korten, Uri Nahum, Pablo Sinues, Sven Schulzke, Oliver Fuchs, Philipp Latzin, Martin Röösli, and Urs Frey; on behalf of the BILD study group
pp. 99–107
Abstract | Full Text | PDF (671 KB) | related editorial 

Sleep and Control of Ventilation

Sleep Apnea–Specific Hypoxic Burden, Symptom Subtypes, and Risk of Cardiovascular Events and All-Cause Mortality
Wojciech Trzepizur, Margaux Blanchard, Timothée Ganem, Frédéric Balusson, Mathieu Feuilloy, Jean-Marc Girault, Nicole Meslier, Emmanuel Oger, Audrey Paris, Thierry Pigeanne, Jean-Louis Racineux, AbdelKebir Sabil, Chloé Gervès-Pinquié, and Frédéric Gagnadoux; on behalf of the ERMES study group
pp. 108–117
Abstract | Full Text | PDF (1185 KB) | related editorial 

Beyond the Blue: What Fellows Are Reading in Other Journals

Phenotypic Heterogeneity in Chronic Obstructive Pulmonary Disease
Malvika Kaul, Solomon Krow, Ai-Yui M. Tan, and Sunit Singla
pp. 118–120
First Page | Full Text | PDF (510 KB) 

Images in Pulmonary, Critical Care, Sleep Medicine and the Sciences

The Bronchial Circulation in COVID-19 Pneumonia
Maximilian Ackermann, Paul Tafforeau, Willi L. Wagner, Claire L. Walsh, Christopher Werlein, Mark P. Kühnel, Florian P. Länger, Catherine Disney, Andrew J. Bodey, Alexandre Bellier, Stijn E. Verleden, Peter D. Lee, Steven J. Mentzer, and Danny D. Jonigk
pp. 121–125
First Page | Full Text | PDF (4894 KB) 
Amyloid Nodules Masquerading as Multifocal Lung Cancer
Silva Kristo, Tianle Zou, Elizabeth U. Dexter, and Saraswati Pokharel
pp. e1–e3
First Page | Full Text | PDF (2316 KB) 

Correspondence

Decreased Fatty Acid Oxidation and Altered Lactate Production during Exercise in Patients with Post-acute COVID-19 Syndrome
Esther de Boer, Irina Petrache, Nir M. Goldstein, J. Tod Olin, Rebecca C. Keith, Brian Modena, Michael P. Mohning, Zulma X. Yunt, Inigo San-Millán, and Jeffrey J. Swigris
pp. 126–129
First Page | Full Text | PDF (660 KB) 
Combustible and Electronic Cigarette Exposures Increase ACE2 Activity and SARS-CoV-2 Spike Binding
Arunava Ghosh, Vishruth Girish, Monet Lou Yuan, Raymond D. Coakley, Joe A. Wrennall, Neil E. Alexis, Erin L. Sausville, Anand Vasudevan, Alexander R. Chait, Jason M. Sheltzer, and Robert Tarran
pp. 129–133
First Page | Full Text | PDF (1550 KB) 
Contrast-enhanced Magnetic Resonance Imaging Does Not Detect a Progression in Lung Morphological Score in Preschool Children with Cystic Fibrosis
Gaël Dournes, Ilyes Benlala, and François Laurent
p. 134
First Page | Full Text | PDF (543 KB) 
Reply to Dournes et al.: Contrast-enhanced Magnetic Resonance Imaging Does Not Detect a Progression in Lung Morphological Score in Preschool Children with Cystic Fibrosis
Mirjam Stahl, Eva Steinke, Mark O. Wielpütz, and Marcus A. Mall; on behalf of all the authors
pp. 134–136
First Page | Full Text | PDF (562 KB) 

Patient Education/Information Series

Climate Change Health Effects and What You Can Do
Sharon Chinthrajah, Erika Garcia, Zainab Hasan, Angela Hy, and Lauren Wong
pp. P1–P2
First Page | PDF (389 KB) 
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