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Publication Cover

American Journal of Respiratory and Critical Care Medicine

Table of Contents
Volume 191, Issue 9 | May 1 2015
ISSN: 1073-449X | eISSN: 1535-4970
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Editorials

Revisiting “Good” and “Bad” Cholesterol. The Battle over Flow through Arteries Now Shifts to Flow through Airways
Michael B. Fessler
pp. 969–970
First Page | Full Text | PDF (450 KB) | related article 
Walking a Tightrope: Targeting Neutrophils to Treat Chronic Obstructive Pulmonary Disease
Shawn D. Aaron
pp. 971–972
First Page | Full Text | PDF (434 KB) | related article 
Finding the Key to Dialysis Catheter Lock
Stephanie C. Shieh and Kathleen D. Liu
pp. 972–974
First Page | Full Text | PDF (445 KB) | related article 
Nighttime in the Intensive Care Unit. A Lens into the Value of Critical Care Delivery
Scott D. Halpern
pp. 974–975
First Page | Full Text | PDF (432 KB) | related article 
Addressing a Challenge with a Challenge. Investigating Respiratory Syncytial Virus Immunity with the Human Challenge Model
Ann R. Falsey
pp. 975–977
First Page | Full Text | PDF (443 KB) | related article 
Finishing What They Started: When Do Researchers’ Responsibilities End?
Dick Menzies
pp. 977–978
First Page | Full Text | PDF (432 KB) | related article 

Concise Clinical Review

Sleep-disordered Breathing in Neuromuscular Disease
Loutfi S. Aboussouan
pp. 979–989
Abstract | Full Text | PDF (1031 KB) 

Original Article

Asthma and Allergy

Serum Apolipoprotein A-I and Large High-Density Lipoprotein Particles Are Positively Correlated with FEV1 in Atopic Asthma
Amisha V. Barochia, Maryann Kaler, Rosemarie A. Cuento, Elizabeth M. Gordon, Nargues A. Weir, Maureen Sampson, Joseph R. Fontana, Sandra MacDonald, Joel Moss, Vincent Manganiello, Alan T. Remaley, and Stewart J. Levine
pp. 990–1000
Abstract | Full Text | PDF (1028 KB) | related editorial 

Chronic Obstructive Pulmonary Disease

CXCR2 Antagonist MK-7123. A Phase 2 Proof-of-Concept Trial for Chronic Obstructive Pulmonary Disease
Stephen I. Rennard, David C. Dale, James F. Donohue, Frank Kanniess, Helgo Magnussen, E. Rand Sutherland, Henrik Watz, Susan Lu, Paul Stryszak, Elizabeth Rosenberg, and Heribert Staudinger
pp. 1001–1011
Abstract | Full Text | PDF (954 KB) | related editorial 
Targeting PI3K-p110α Suppresses Influenza Virus Infection in Chronic Obstructive Pulmonary Disease
Alan Chen-Yu Hsu, Malcolm R. Starkey, Irwan Hanish, Kristy Parsons, Tatt Jhong Haw, Linda J. Howland, Ian Barr, James B. Mahony, Paul S. Foster, Darryl A. Knight, Peter A. Wark, and Philip M. Hansbro
pp. 1012–1023
Abstract | Full Text | PDF (1031 KB) 

Critical Care

Ethanol Lock and Risk of Hemodialysis Catheter Infection in Critically Ill Patients. A Randomized Controlled Trial
Bertrand Souweine, Alexandre Lautrette, Didier Gruson, Emmanuel Canet, Kada Klouche, Laurent Argaud, Julien Bohe, Maïté Garrouste-Orgeas, Christophe Mariat, François Vincent, Sophie Cayot, Olivier Cointault, Alain Lepape, Dominique Guelon, Michael Darmon, Aurélien Vesin, Nicolas Caillot, Carole Schwebel, Alexandre Boyer, Elie Azoulay, Lila Bouadma, and Jean-François Timsit
pp. 1024–1032
Abstract | Full Text | PDF (681 KB) | related editorial 
The Timing of Discharge from the Intensive Care Unit and Subsequent Mortality. A Prospective, Multicenter Study
John D. Santamaria, Graeme J. Duke, David V. Pilcher, D. James Cooper, John Moran, and Rinaldo Bellomo; for the Discharge and Readmission Evaluation (DARE) Study
pp. 1033–1039
Abstract | Full Text | PDF (650 KB) | related editorial 

Pulmonary Infections

Impaired Antibody-mediated Protection and Defective IgA B-Cell Memory in Experimental Infection of Adults with Respiratory Syncytial Virus
Maximillian S. Habibi, Agnieszka Jozwik, Spyridon Makris, Jake Dunning, Allan Paras, John P. DeVincenzo, Cornelis A. M. de Haan, Jens Wrammert, Peter J. M. Openshaw, and Christopher Chiu; The Mechanisms of Severe Acute Influenza Consortium Investigators
pp. 1040–1049
Abstract | Full Text | PDF (980 KB) | related editorial 

Pulmonary Vascular Disease

The Effects of Exercise on Right Ventricular Contractility and Right Ventricular–Arterial Coupling in Pulmonary Hypertension
Onno A. Spruijt, Frances S. de Man, Herman Groepenhoff, Frank Oosterveer, Nico Westerhof, Anton Vonk-Noordegraaf, and Harm-Jan Bogaard
pp. 1050–1057
Abstract | Full Text | PDF (691 KB) 

Tuberculosis and Mycobacterial Disease

A Dose-Ranging Trial to Optimize the Dose of Rifampin in the Treatment of Tuberculosis
Martin J. Boeree, Andreas H. Diacon, Rodney Dawson, Kim Narunsky, Jeannine du Bois, Amour Venter, Patrick P. J. Phillips, Stephen H. Gillespie, Timothy D. McHugh, Michael Hoelscher, Norbert Heinrich, Sunita Rehal, Dick van Soolingen, Jakko van Ingen, Cecile Magis-Escurra, David Burger, Georgette Plemper van Balen, and Rob E. Aarnoutse; on behalf of the PanACEA Consortium
pp. 1058–1065
Abstract | Full Text | PDF (850 KB) | related editorial 

American Thoracic Society Documents

Official American Thoracic Society Technical Standards: Flexible Airway Endoscopy in Children
Albert Faro, Robert E. Wood, Michael S. Schechter, Albin B. Leong, Eric Wittkugel, Kathy Abode, James F. Chmiel, Cori Daines, Stephanie Davis, Ernst Eber, Charles Huddleston, Todd Kilbaugh, Geoffrey Kurland, Fabio Midulla, David Molter, Gregory S. Montgomery, George Retsch-Bogart, Michael J. Rutter, Gary Visner, Stephen A. Walczak, Thomas W. Ferkol, and Peter H. Michelson; on behalf of the American Thoracic Society Ad Hoc Committee on Flexible Airway Endoscopy in Children
pp. 1066–1080
Abstract | Full Text | PDF (615 KB) 

Beyond the Blue: What Fellows Are Reading in Other Journals

New Insights in Chronic Obstructive Pulmonary Disease and Comorbidity
Fiona Cleutjens, Filip Triest, Sarah Wilke, Lowie E. G. W. Vanfleteren, Frits M. E. Franssen, Daisy J. A. Janssen, Erica P. Rutten, Martijn A. Spruit, and Emiel F. M. Wouters
pp. 1081–1082
First Page | Full Text | PDF (497 KB) 

Images in Pulmonary, Critical Care, Sleep Medicine and the Sciences

Left Pulmonary Agenesis Showing Extraordinary Chest X-Ray Findings
Motoyasu Sagawa, Yuichiro Machida, Makoto Tanaka, Nozomu Motono, Sumiko Maeda, Tsutomu Sakuma, and Katsuo Usuda
p. 1083
First Page | Full Text | PDF (535 KB) 

Correspondence

Parametric Response Mapping Adds Value to Current Computed Tomography Biomarkers in Diagnosing Chronic Obstructive Pulmonary Disease
Esther Pompe, Eva M. van Rikxoort, Michael Schmidt, Jan Rühaak, Leticia Gallardo Estrella, Rozemarijn Vliegenthart, Matthijs Oudkerk, Harry J. de Koning, Bram van Ginneken, Pim A. de Jong, Jan-Willem J. Lammers, and Firdaus A. A. Mohamed Hoesein
pp. 1084–1086
First Page | Full Text | PDF (827 KB) 
Electronic Nose Identifies Bronchoalveolar Lavage Fluid Eosinophils in Asthma
Niki Fens, Koenraad F. van der Sluijs, Marianne A. van de Pol, Annemiek Dijkhuis, Barbara S. Smids, Jaring S. van der Zee, René Lutter, Aeilko H. Zwinderman, and Peter J. Sterk; RESOLVE Research Team
pp. 1086–1088
First Page | Full Text | PDF (520 KB) 
Imaging Neutrophil Extracellular Traps in the Alveolar Space and Pulmonary Capillaries of a Murine Sepsis Model by Multiphoton Microscopy
Koji Tanaka, Yuji Toiyama, Yasuhiro Inoue, Toshimitsu Araki, Yasuhiko Mohri, Akira Mizoguchi, and Masato Kusunoki
pp. 1088–1089
First Page | Full Text | PDF (432 KB) 
Reply: Neutrophil Extracellular Traps in Primary Graft Dysfunction after Lung Transplantation
David M. Sayah, Beñat Mallavia, and Mark R. Looney
p. 1089
First Page | Full Text | PDF (420 KB) 
Mistaken Step-Up Units
Pablo Monedero
pp. 1089–1090
First Page | Full Text | PDF (423 KB) 

Patient Information Series

Flexible Bronchoscopy
pp. P7–P8
First Page | PDF (256 KB) 
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