American Journal of Respiratory and Critical Care Medicine

Shivam Singh, Sunita Kularia, Shivakshi Shukla, Mithilesh Singh, Manish Kumar, Ashish Kumar Sharma. (2025) A current review on animal models of anti-asthmatic drugs screening. Frontiers in Pharmacology 16.
Online publication date: 28-Jan-2025.
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Kai Pan, Qiong Li, Zhikun Guo, Zongjin Li. (2025) Healing action of Interleukin-4 (IL-4) in acute and chronic inflammatory conditions: Mechanisms and therapeutic strategies. Pharmacology & Therapeutics 265, 108760.
Online publication date: 1-Jan-2025.
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Sofi Vassileva, Peter Bonta, Els Weersink, Ian Pavord, Bart Hilvering. 2025. Biological Therapies to Treat Allergy and Asthma. Reference Module in Life Sciences.
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Irfan Ullah, Hyo Sung Choi, Changseon Choi, Kunho Chung, Jae Wook Jung, Gyeongju Yun, Seoyoun Heo, Yujong Yi, Eunhwa Kang, Sang-Heon Kim, Ho Joo Yoon, Taiyoun Rhim, Sang-Kyung Lee. (2024) Targeted siRNA delivery to lung epithelia reduces airway inflammation in a mouse model of allergic asthma. Biotechnology and Bioprocess Engineering 29:1, 97-108.
Online publication date: 21-Feb-2024.
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Avik Sarkar, Sahithi Reddy Narala, Kalpana Panati, Venkata Ramireddy Narala. 2024. Chemical therapies, immunotherapy, and new treatment strategies for allergic asthma. Allergic Asthma: Immunopathogenesis, 117-166.
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Joon-Pyo Hong, Sung Hun Kang, Jinah Chu, Sun-Ju Byeon, Hyunjoo Lee, Jeong-Hee Choi, Kyung Chul Lee, Seok Jin Hong. (2023) The Relationship Between Zonulin and Asthma: A Mouse Model Study. Journal of Rhinology 30:3, 161-166.
Online publication date: 30-Nov-2023.
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Ilja Striz, Kornel Golebski, Zuzana Strizova, Stelios Loukides, Petros Bakakos, Nicola A. Hanania, Milos Jesenak, Zuzana Diamant. (2023) New insights into the pathophysiology and therapeutic targets of asthma and comorbid chronic rhinosinusitis with or without nasal polyposis. Clinical Science 137:9, 727-753.
Online publication date: 18-May-2023.
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Yuan Wu, Mengfen Huang, Jinyao Zhong, Yue Lu, Kao Gan, Rongyuan Yang, Yuntao Liu, Jiqiang Li, Jiankun Chen. (2023) The clinical efficacy of type 2 monoclonal antibodies in eosinophil-associated chronic airway diseases: a meta-analysis. Frontiers in Immunology 14.
Online publication date: 11-Apr-2023.
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Gabriele Matschiner, Mary F. Fitzgerald, Ulrich Moebius, Andreas M. Hohlbaum, Hendrik Gille, Kristian Jensen, Klaus Kirchfeld, Barbara Rattenstetter, Alice Laforge, Rachida S. Bel Aiba, Joe Ciccotosto, Hong Nyugen, Martyn L. Foster, John N. Snouwaert, MyTrang Nguyen, Beverly H. Koller, Louis Matis, Gary P. Anderson, Shane A. Olwill. (2023) Elarekibep (PRS-060/AZD1402), a new class of inhaled Anticalin medicine targeting IL-4Ra for type 2 endotype asthma. Journal of Allergy and Clinical Immunology 151:4, 966-975.
Online publication date: 1-Apr-2023.
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James E. Gern, Ian D. Pavord. (2023) Challenges and Opportunities in Asthma Prevention and Treatment. The Journal of Allergy and Clinical Immunology: In Practice 11:3, 748-749.
Online publication date: 1-Mar-2023.
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Laurent Guilleminault, Eva Conde, Laurent L. Reber. (2022) Pharmacological approaches to target type 2 cytokines in asthma. Pharmacology & Therapeutics 237, 108167.
Online publication date: 1-Sep-2022.
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, Hugo A Farne, Amanda Wilson, Stephen Milan, Emma Banchoff, Freda Yang, Colin VE Powell. (2022) Anti-IL-5 therapies for asthma. Cochrane Database of Systematic Reviews 2022:7.
Online publication date: 12-Jul-2022.
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Mala Upadhyay, Antoine Nehme, Samiksha Wasnik. (2022) Title-Inflammatory Signaling Pathways in Allergic and Infection-Associated Lung Diseases. Allergies 2:2, 57-74.
Online publication date: 1-Jun-2022.
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Richard T. AMISON, Clive P. PAGE. (2022) Novel pharmacological therapies for the treatment of bronchial asthma. Minerva Medica 113:1.
Online publication date: 1-Feb-2022.
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Brittany Salter, Paige Lacy, Manali Mukherjee. (2022) Biologics in Asthma: A Molecular Perspective to Precision Medicine. Frontiers in Pharmacology 12.
Online publication date: 19-Jan-2022.
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Simon Couillard, Ian D. Pavord. 2022. Biological Therapies for Asthma. Encyclopedia of Respiratory Medicine, 411-434.
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Luciana Pádua Tavares, Izabela Galvão, Maximiliano R Ferrero. 2022. Novel Immunomodulatory Therapies for Respiratory Pathologies. Comprehensive Pharmacology, 554-594.
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Soyoon Sim, Youngwoo Choi, Hae-Sim Park. (2022) Immunologic Basis of Type 2 Biologics for Severe Asthma. Immune Network 22:6.
Online publication date: 1-Jan-2022.
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Siti Muhamad Nur Husna, Norasnieda Md Shukri, Noor Suryani Mohd Ashari, Kah Keng Wong. (2022) IL-4/IL-13 axis as therapeutic targets in allergic rhinitis and asthma. PeerJ 10, e13444.
Online publication date: 30-May-2022.
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, Andrew Gallagher, Michaela Edwards, Parameswaran Nair, Stewart Drew, Aashish Vyas, Rashmi Sharma, Paul A Marsden, Ran Wang, David JW Evans. (2021) Anti-interleukin-13 and anti-interleukin-4 agents versus placebo, anti-interleukin-5 or anti-immunoglobulin-E agents, for people with asthma. Cochrane Database of Systematic Reviews 2021:10.
Online publication date: 19-Oct-2021.
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Dominick E Shaw, Liam G Heaney, Mike Thomas, Richard Beasley, Peter G Gibson, Ian D Pavord. (2021) Balancing the needs of the many and the few: where next for adult asthma guidelines?. The Lancet Respiratory Medicine 9:7, 786-794.
Online publication date: 1-Jul-2021.
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Norihiro Harada, Jun Ito, Kazuhisa Takahashi. (2021) Clinical effects and immune modulation of biologics in asthma. Respiratory Investigation 59:4, 389-396.
Online publication date: 1-Jul-2021.
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Klimek L, Hagemann J, Casper I, Huppertz T, Bedbrook A, Bousquet J. (2021) Immunological background for treatments with biologicals in CRSwNP. Archives of Asthma, Allergy and Immunology 5:1, 022-029.
Online publication date: 8-Apr-2021.
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Beatriz León, Andre Ballesteros-Tato. (2021) Modulating Th2 Cell Immunity for the Treatment of Asthma. Frontiers in Immunology 12.
Online publication date: 10-Feb-2021.
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Nozomi Tani, Nobutaka Kataoka, Yusuke Kunimatsu, Yusuke Tachibana, Takumi Sugimoto, Izumi Sato, Yuri Ogura, Kazuki Hirose, Takayuki Takeda. (2021) Early responders within seven days of dupilumab treatment for severe asthma evaluated by patient-reported outcome: a pilot study. Multidisciplinary Respiratory Medicine 16.
Online publication date: 17-Mar-2021.
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Archita Ray, Sabita Singh, Joytri Dutta, Ulaganathan Mabalirajan. 2021. Targeting Molecular and Cellular Mechanisms in Asthma. Targeting Cellular Signalling Pathways in Lung Diseases, 27-51.
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John Foerster, Aleksandra Molęda. (2020) Virus-Like Particle-Mediated Vaccination against Interleukin-13 May Harbour General Anti-Allergic Potential beyond Atopic Dermatitis. Viruses 12:4, 438.
Online publication date: 13-Apr-2020.
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Angela Moran, Ian D Pavord. (2020) Anti-IL-4/IL-13 for the treatment of asthma: the story so far. Expert Opinion on Biological Therapy 20:3, 283-294.
Online publication date: 20-Jan-2020.
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Julie K. Nguyen, Evan Austin, Alisen Huang, Andrew Mamalis, Jared Jagdeo. (2020) The IL-4/IL-13 axis in skin fibrosis and scarring: mechanistic concepts and therapeutic targets. Archives of Dermatological Research 312:2, 81-92.
Online publication date: 6-Sep-2019.
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Michael C Peters, Sally E Wenzel. (2020) Intersection of biology and therapeutics: type 2 targeted therapeutics for adult asthma. The Lancet 395:10221, 371-383.
Online publication date: 1-Feb-2020.
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N.O. Pereverzina, L.S. Kruglova, I.E. Musaev. (2020) Present and future in the treatment of chronic spontaneous urticaria. Klinicheskaya dermatologiya i venerologiya 19:5, 604.
Online publication date: 1-Jan-2020.
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Ludger Klimek, Boris A. Stuck, Barbara Wollenberg. (2020) Chronische Rhinosinusitis mit Nasenpolypen: Biologika auf dem Prüfstand. Deutsches Ärzteblatt Online.
Online publication date: 14-Feb-2020.
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O. M. Kurbacheva, M. A. Galitskaya. (2019) The place of Omalizumab in the treatment of allergic diseases. Medical Council:15, 38-49.
Online publication date: 8-Dec-2019.
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Babak Aberumand, Anne K. Ellis. (2019) Asthma and the Biologics Revolution, Part 2: Failures and the Future Potential. Current Treatment Options in Allergy 6:4, 468-492.
Online publication date: 16-Nov-2019.
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Jung-Eun Kim, Keunok Jung, Jeong-Ah Kim, Seung-Hyun Kim, Hae-Sim Park, Yong-Sung Kim. (2019) Engineering of anti-human interleukin-4 receptor alpha antibodies with potent antagonistic activity. Scientific Reports 9:1.
Online publication date: 23-May-2019.
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Yorihiko Kyogoku, Hisatoshi Sugiura, Tomohiro Ichikawa, Tadahisa Numakura, Akira Koarai, Mitsuhiro Yamada, Naoya Fujino, Yutaka Tojo, Katsuhiro Onodera, Rie Tanaka, Kei Sato, Hirohito Sano, Shun Yamanaka, Koji Itakura, Ayumi Mitsune, Tsutomu Tamada, Takaaki Akaike, Masakazu Ichinose. (2019) Nitrosative stress in patients with asthma–chronic obstructive pulmonary disease overlap. Journal of Allergy and Clinical Immunology 144:4, 972-983.e14.
Online publication date: 1-Oct-2019.
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Ian D. Pavord, Rahul Shrimanker, Nicola A. Hanania. 2019. Biologics targeting type 2 inflammation in severe asthma. Severe Asthma.
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Matshediso C. Mokoka, Melissa J. McDonnell, Elaine MacHale, Breda Cushen, Fiona Boland, Sarah Cormican, Christina Doherty, Frank Doyle, Richard W. Costello, Garrett Greene. (2019) Inadequate assessment of adherence to maintenance medication leads to loss of power and increased costs in trials of severe asthma therapy: results from a systematic literature review and modelling study. European Respiratory Journal 53:5, 1802161.
Online publication date: 7-Mar-2019.
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Bart N. Lambrecht, Hamida Hammad, John V. Fahy. (2019) The Cytokines of Asthma. Immunity 50:4, 975-991.
Online publication date: 1-Apr-2019.
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Willem van de Veen, Mübeccel Akdis. (2019) The use of biologics for immune modulation in allergic disease. Journal of Clinical Investigation 129:4, 1452-1462.
Online publication date: 18-Mar-2019.
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R. Stokes Peebles, Mark A. Aronica. (2019) Proinflammatory Pathways in the Pathogenesis of Asthma. Clinics in Chest Medicine 40:1, 29-50.
Online publication date: 1-Mar-2019.
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. (2019) Role of Biologics in Asthma. American Journal of Respiratory and Critical Care Medicine 199:4, 433-445.
Online publication date: 15-Feb-2019.
Abstract | Full Text | PDF (1346 KB) | Supplemental Material 
Jae Seok Jeong, So Ri Kim, Seong Ho Cho, Yong Chul Lee. (2019) A Novel Insight on Endotyping Heterogeneous Severe Asthma Based on Endoplasmic Reticulum Stress: Beyond the “Type 2/Non-Type 2 Dichotomy”. International Journal of Molecular Sciences 20:3, 713.
Online publication date: 7-Feb-2019.
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L. Klimek, M. Koennecke, J. Hagemann, B. Wollenberg, S. Becker. (2019) Immunologie der Polyposis nasi als Grundlage für eine Therapie mit Biologicals. HNO 67:1, 15-26.
Online publication date: 30-Aug-2018.
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Kamyar M. Hedayat, Jean-Claude Lapraz. 2019. Asthma: An integrative physiologic approach. The Theory of Endobiogeny, 23-53.
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Olga Danov, Sharon Melissa Jiménez Delgado, Helena Obernolte, Sophie Seehase, Susann Dehmel, Peter Braubach, Hans-Gerd Fieguth, Gabriele Matschiner, Mary Fitzgerald, Danny Jonigk, Sascha Knauf, Olaf Pfennig, Gregor Warnecke, Judy Wichmann, Armin Braun, Katherina Sewald, Hong Wei Chu. (2018) Human lung tissue provides highly relevant data about efficacy of new anti-asthmatic drugs. PLOS ONE 13:11, e0207767.
Online publication date: 30-Nov-2018.
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Wirach Chitsuthipakorn, Kachorn Seresirikachorn, Doron D. Sommer, Tobial McHugh, Kornkiat Snidvongs. (2018) Endotypes of Chronic Rhinosinusitis Across Ancestry and Geographic Regions. Current Allergy and Asthma Reports 18:9.
Online publication date: 11-Jul-2018.
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Gail M. Gauvreau, Beth E. Davis, John Paul Oliveria. 2018. Inhaled Antisense for Treatment of Respiratory Disease. Oligonucleotide‐Based Drugs and Therapeutics, 355-388.
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Danielle Karo-Atar, Almog Bitton, Itai Benhar, Ariel Munitz. (2018) Therapeutic Targeting of the Interleukin-4/Interleukin-13 Signaling Pathway: In Allergy and Beyond. BioDrugs 32:3, 201-220.
Online publication date: 7-May-2018.
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Martin Braddock, Nicola A. Hanania, Amir Sharafkhaneh, Gene Colice, Mats Carlsson. (2018) Potential Risks Related to Modulating Interleukin-13 and Interleukin-4 Signalling: A Systematic Review. Drug Safety 41:5, 489-509.
Online publication date: 6-Feb-2018.
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Juliana Barrios, Xingbin Ai. (2018) Neurotrophins in Asthma. Current Allergy and Asthma Reports 18:2.
Online publication date: 16-Feb-2018.
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So Ri Kim. 2018. Pharmacologic Therapies for Severe Asthma. Severe Asthma, 99-122.
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Fang Chen, Jia-Ying Zhang, Hong-Kuan Yang, Fang Wang. 2018. Asthma Precision. Genomic Approach to Asthma, 361-385.
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Jae Seok Jeong, So Ri Kim, Seong Ho Cho, Yong Chul Lee. (2017) Endoplasmic Reticulum Stress and Allergic Diseases. Current Allergy and Asthma Reports 17:12.
Online publication date: 8-Nov-2017.
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Hugo A Farne, Amanda Wilson, Colin Powell, Lynne Bax, Stephen J Milan, . (2017) Anti-IL5 therapies for asthma. Cochrane Database of Systematic Reviews 44.
Online publication date: 21-Sep-2017.
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Michael Wegmann. (2017) Targeting cytokines in asthma therapy: could IL-37 be a solution?. Expert Review of Respiratory Medicine 11:9, 675-677.
Online publication date: 17-Jul-2017.
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Peter A. Tauber, Winfried F. Pickl. (2017) Pharmacological targeting of allergen-specific T lymphocytes. Immunology Letters 189, 27-39.
Online publication date: 1-Sep-2017.
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Seyyed Shamsadin Athari, Seyyede Masoume Athari, Fateme Beyzay, Masoud Movassaghi, Esmaeil Mortaz, Mehdi Taghavi. (2017) Critical role of Toll-like receptors in pathophysiology of allergic asthma. European Journal of Pharmacology 808, 21-27.
Online publication date: 1-Aug-2017.
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Fedoseev GB. (2017) The Role of Cytokines in the Pathogenesis of Bronchial Asthma and the Possibilities of Anti-Cytokine Therapy. Journal of Lung, Pulmonary & Respiratory Research 4:4.
Online publication date: 27-Jul-2017.
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Catherine S. Tripp, Carolyn Cuff, Andrew L. Campbell, Barbara A. Hendrickson, Jeff Voss, Terry Melim, Chengbin Wu, Andrew D. Cherniack, Kenneth Kim. (2017) RPC4046, A Novel Anti-interleukin-13 Antibody, Blocks IL-13 Binding to IL-13 α1 and α2 Receptors: A Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation First-in-Human Study. Advances in Therapy 34:6, 1364-1381.
Online publication date: 28-Apr-2017.
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Matthew Loxham, Donna E. Davies. (2017) Phenotypic and genetic aspects of epithelial barrier function in asthmatic patients. Journal of Allergy and Clinical Immunology 139:6, 1736-1751.
Online publication date: 1-Jun-2017.
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Namita A. Gandhi, Gianluca Pirozzi, Neil M. H. Graham. (2017) Commonality of the IL-4/IL-13 pathway in atopic diseases. Expert Review of Clinical Immunology 13:5, 425-437.
Online publication date: 15-Mar-2017.
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Giuseppe Santini, Nadia Mores, Mario Malerba, Chiara Mondino, Roberta Anzivino, Giuseppe Macis, Paolo Montuschi. (2017) Dupilumab for the treatment of asthma. Expert Opinion on Investigational Drugs 26:3, 357-366.
Online publication date: 7-Feb-2017.
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Maria Theresa D. Opina, Wendy C. Moore. (2017) Phenotype-Driven Therapeutics in Severe Asthma. Current Allergy and Asthma Reports 17:2.
Online publication date: 23-Feb-2017.
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Hun Soo Chang, Tae-Hyeong Lee, Ji Ae Jun, Ae Rin Baek, Jong-Sook Park, So-My Koo, Yang- Ki Kim, Ho Sung Lee, Choon-Sik Park. (2017) Neutrophilic inflammation in asthma: mechanisms and therapeutic considerations. Expert Review of Respiratory Medicine 11:1, 29-40.
Online publication date: 15-Dec-2016.
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Ulrich M. Zissler. 2017. Specific Therapies for Asthma Endotypes: A New Twist in Drug Development. Allergy Prevention and Exacerbation, 209-238.
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Linda Swedin, Tiiu Saarne, Maria Rehnberg, Pernilla Glader, Magdalena Niedzielska, Gustav Johansson, Petra Hazon, Matthew C. Catley. (2017) Patient stratification and the unmet need in asthma. Pharmacology & Therapeutics 169, 13-34.
Online publication date: 1-Jan-2017.
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I. P. Shilovskiy, D. V. Eroshkina, A. A. Babakhin, M. R. Khaitov. (2017) Anticytokine therapy of allergic asthma. Molecular Biology 51:1, 1-13.
Online publication date: 23-Feb-2017.
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Merritt L. Fajt, Sally E. Wenzel. (2017) Development of New Therapies for Severe Asthma. Allergy, Asthma & Immunology Research 9:1, 3.
Online publication date: 1-Jan-2017.
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G B Fedoseev, V I Trofimov, K V Negrutsa, V G Timchik, V I Golubeva, V A Aleksandrin, T S Razumovskaya, K N Kryakunov. (2016) Regarding to the issue of the role of cytokines in the pathogenesis of asthma and the possibilities of anticytokine therapy. Russian Journal of Allergy 13:6, 23-36.
Online publication date: 15-Dec-2016.
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Andrea C Valladao, Charles W Frevert, Lisa K Koch, Daniel J Campbell, Steven F Ziegler. (2016) STAT6 Regulates the Development of Eosinophilic versus Neutrophilic Asthma in Response to Alternaria alternata. The Journal of Immunology 197:12, 4541-4551.
Online publication date: 15-Dec-2016.
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Amy Chang, Ynuk Bossé. (2016) Targeting Single Molecules in Asthma Benefits Few. Trends in Molecular Medicine 22:11, 935-945.
Online publication date: 1-Nov-2016.
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Diane Wang, Lisa A. Beck. (2016) Immunologic Targets in Atopic Dermatitis and Emerging Therapies: An Update. American Journal of Clinical Dermatology 17:5, 425-443.
Online publication date: 1-Jul-2016.
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Rabih Halwani, Asma Sultana Shaik, Elaref Ratemi, Sibtain Afzal, Rosan Kenana, Saleh Al-Muhsen, Achraf Al Faraj. (2016) A novel anti-IL4Rα nanoparticle efficiently controls lung inflammation during asthma. Experimental & Molecular Medicine 48:10, e262-e262.
Online publication date: 7-Oct-2016.
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Kent Lam, Robert C. Kern, Amber Luong. (2016) Is there a future for biologics in the management of chronic rhinosinusitis?. International Forum of Allergy & Rhinology 6:9, 935-942.
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Larry Borish. (2016) The immunology of asthma. Annals of Allergy, Asthma & Immunology 117:2, 108-114.
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Ian D. Pavord, Bart Hilvering, Rahul Shrimanker. (2016) Emerging Biologics in Severe Asthma. Immunology and Allergy Clinics of North America 36:3, 609-623.
Online publication date: 1-Aug-2016.
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Achraf Al Faraj, Asma Sultana Shaik, Sibtain Afzal, Saleh Al‐Muhsen, Rabih Halwani. (2016) Specific targeting and noninvasive magnetic resonance imaging of an asthma biomarker in the lung using polyethylene glycol functionalized magnetic nanocarriers. Contrast Media & Molecular Imaging 11:3, 172-183.
Online publication date: 28-Dec-2015.
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Melissa H. Bloodworth, Dawn C. Newcomb, Daniel E. Dulek, Matthew T. Stier, Jacqueline Y. Cephus, Jian Zhang, Kasia Goleniewska, Jay K. Kolls, R. Stokes Peebles, S. Ehrt. (2016) STAT6 Signaling Attenuates Interleukin-17-Producing γδ T Cells during Acute Klebsiella pneumoniae Infection. Infection and Immunity 84:5, 1548-1555.
Online publication date: 1-May-2016.
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Panida Sriaroon, Mark Ballow. (2016) Biological Modulators in Eosinophilic Diseases. Clinical Reviews in Allergy & Immunology 50:2, 252-272.
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Gilda Varricchi, Diego Bagnasco, Francesco Borriello, Enrico Heffler, Giorgio W. Canonica. (2016) Interleukin-5 pathway inhibition in the treatment of eosinophilic respiratory disorders. Current Opinion in Allergy & Clinical Immunology 16:2, 186-200.
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Hesham Raafat. (2016) Biological therapy in severe asthma: A gem or a jam. Egyptian Journal of Bronchology 10:1, 1-4.
Online publication date: 17-Feb-2016.
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Kara Vale. (2016) Targeting the Jak-Stat Pathway in the Treatment of ‘Th2-High’ Severe Asthma. Future Medicinal Chemistry 8:4, 405-419.
Online publication date: 2-Mar-2016.
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Jimena Perez-Lloret, Isobel S. Okoye, Riccardo Guidi, Yashaswini Kannan, Stephanie M. Coomes, Stephanie Czieso, Gabrielle Mengus, Irwin Davidson, Mark S. Wilson. (2016) T-cell–intrinsic Tif1α/Trim24 regulates IL-1R expression on T H 2 cells and T H 2 cell-mediated airway allergy. Proceedings of the National Academy of Sciences 113:5.
Online publication date: 19-Jan-2016.
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Kian Fan Chung. (2016) Asthma phenotyping: a necessity for improved therapeutic precision and new targeted therapies. Journal of Internal Medicine 279:2, 192-204.
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Tracy L Staton, David F Choy, Joseph R Arron. (2016) Biomarkers in the Clinical Development of Asthma Therapies. Biomarkers in Medicine 10:2, 165-176.
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Laura De Ferrari, Alessandra Chiappori, Diego Bagnasco, Anna Maria Riccio, Giovanni Passalacqua, Giorgio Walter Canonica. (2016) Molecular phenotyping and biomarker development: are we on our way towards targeted therapy for severe asthma?. Expert Review of Respiratory Medicine 10:1, 29-38.
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PD Mitchell, AI El‐Gammal, PM O'Byrne. (2016) Emerging monoclonal antibodies as targeted innovative therapeutic approaches to asthma. Clinical Pharmacology & Therapeutics 99:1, 38-48.
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Patrick D. Mitchell, Amani I. El-Gammal, Paul M. O’Byrne. 2016. Anti-IgE and Biologic Approaches for the Treatment of Asthma. Pharmacology and Therapeutics of Asthma and COPD, 131-152.
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Chrysanthi Skevaki, Christoph Hudemann, Harald Renz. 2016. Interleukin 4 and the Related Cytokines (Interleukin 5 and Interleukin 13). Compendium of Inflammatory Diseases, 678-686.
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Fernando O. Martinez Estrada, Siamon Gordon. 2016. The Cellular and Molecular Network of IL-4 and IL-13. Encyclopedia of Immunobiology, 519-524.
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Bart Hilvering, Ian D. Pavord. 2016. Biologicals to Treat Allergy and Asthma. Encyclopedia of Immunobiology, 321-327.
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Andrew L. Durham, Gaetano Caramori, Kian F. Chung, Ian M. Adcock. (2016) Targeted anti-inflammatory therapeutics in asthma and chronic obstructive lung disease. Translational Research 167:1, 192-203.
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Namita A. Gandhi, Brandy L. Bennett, Neil M. H. Graham, Gianluca Pirozzi, Neil Stahl, George D. Yancopoulos. (2016) Targeting key proximal drivers of type 2 inflammation in disease. Nature Reviews Drug Discovery 15:1, 35-50.
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Nestor A Molfino, Piotr Kuna, Jonathan A Leff, Chad K Oh, Dave Singh, Marlene Chernow, Brian Sutton, Geoffrey Yarranton. (2016) Phase 2, randomised placebo-controlled trial to evaluate the efficacy and safety of an anti-GM-CSF antibody (KB003) in patients with inadequately controlled asthma. BMJ Open 6:1, e007709.
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Giorgio Walter Canonica, Gianenrico Senna, Patrick D. Mitchell, Paul M. O’Byrne, Giovanni Passalacqua, Gilda Varricchi. (2016) Therapeutic interventions in severe asthma. World Allergy Organization Journal 9, 40.
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Mitsunari NAKAJIMA, Minetaro OGAWA, Yoshiaki AMAKURA, Morio YOSHIMURA, Satoshi OKUYAMA, Yoshiko FURUKAWA. (2016) 3,5,6,7,8,3’,4’-Heptamethoxyflavone reduces interleukin-4 production in the spleen cells of mice . Biomedical Research 37:2, 95-99.
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Kenji Izuhara, Shoichiro Ohta, Junya Ono. (2016) Using Periostin as a Biomarker in the Treatment of Asthma. Allergy, Asthma & Immunology Research 8:6, 491.
Online publication date: 1-Jan-2016.
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Peng Gao, Peter G Gibson, Katherine J Baines, Ian A Yang, John W Upham, Paul N Reynolds, Sandra Hodge, Alan L James, Christine Jenkins, Matthew J Peters, Jie Zhang, Jodie L Simpson. (2015) Anti-inflammatory deficiencies in neutrophilic asthma: reduced galectin-3 and IL-1RA/IL-1β. Respiratory Research 16:1.
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. (2015) Evolving Concepts of Asthma. American Journal of Respiratory and Critical Care Medicine 192:6, 660-668.
Online publication date: 15-Sep-2015.
Abstract | Full Text | PDF (779 KB) | Supplemental Material 
Kian Fan Chung. (2015) Targeting the interleukin pathway in the treatment of asthma. The Lancet 386:9998, 1086-1096.
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Kenji Izuhara, Hisako Matsumoto, Shoichiro Ohta, Junya Ono, Kazuhiko Arima, Masahiro Ogawa. (2015) Recent developments regarding periostin in bronchial asthma. Allergology International 64, S3-S10.
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Richard D. May, Michael Fung. (2015) Strategies targeting the IL-4/IL-13 axes in disease. Cytokine 75:1, 89-116.
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Sarah M. McCormick, Nicola M. Heller. (2015) Commentary: IL-4 and IL-13 receptors and signaling. Cytokine 75:1, 38-50.
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T. B. Casale, J. Cole, E. Beck, C. F. Vogelmeier, J. Willers, C. Lassen, A. Hammann‐Haenni, L. Trokan, P. Saudan, M. E. Wechsler. (2015) CYT 003, a TLR 9 agonist, in persistent allergic asthma – a randomized placebo‐controlled Phase 2b study. Allergy 70:9, 1160-1168.
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Bruce S. Bochner. (2015) Novel Therapies for Eosinophilic Disorders. Immunology and Allergy Clinics of North America 35:3, 577-598.
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