Supported by the U.K. National Institute of Health Research (NIHR) (Z.A.P.), the Batchworth Charitable Trust, the Moulton Charitable Foundation, and the NIHR University College London Hospitals Biomedical Research Centre (UCLH BRC) (A.S.M.), the Research Councils UK (S.D.H.), the NIHR Clinical Research Facility and BRC at Guy’s and St. Thomas’ National Health Service (NHS) Foundation Trust (GSST) and King’s College London (N.H. and B.C.), and by University College London and UCLH BRC (H.E.M., Z.A.P., and A.S.M.). The NIHR doctorate fellowship (2010–2014) underpinned the core patient population study on which this follow-up was built, as did funding from the Batchworth Charitable Trust, Moulton Foundation, and European Society of intensive Care Medicine. Additional funding was received from the Whittington Hospital NHS Trust and the European Society of Intensive Care Medicine.

Author Contributions: Concept and design—Z.A.P., P.S.S., J.M., S.D.H., N.H., and H.E.M.; data collection—Z.A.P., A.S.M., J.R., B.C., and A.R.; analysis and interpretation—Z.A.P., A.S.M., B.C., P.S.S., A.R., J.M., S.D.H., N.H., and H.E.M.; manuscript drafting and revision—Z.A.P., A.S.M., B.C., P.S.S., A.R., J.M., S.D.H., N.H., and H.E.M.

Author disclosures are available with the text of this letter at www.atsjournals.org.